To strengthen the education and assistance of the students with registered cards and promote their growth is the basic "hematopoietic" work to solve the problem of effective connection between poverty alleviation and rural revitalization. In the scene of promoting the great rejuvenation of the Chinese nation with Chinese path to modernization, higher vocational colleges account for half of China's colleges and universities, and have a large number of poor students who have filed cards. It is more important to optimize the education and assistance of students who have filed cards. Based on the case analysis of the N vocational college in South Guangxi, it is found that the communication and visit needs to be deepened, the self-confidence training needs to be strengthened, the award and assistance standards need to be improved, the career planning needs to be advanced, the thanksgiving education needs to be strengthened, and the assistance procedures need to be optimized, which makes the education and assistance of the students who have filed and registered cards do not do well enough . It is necessary not only to improve political and ideological awareness, strengthen ideological and political education, and optimize the design of education and assistance, but also to improve the process of award and assistance, and strengthen the evaluation of the effectiveness of assistance, so as to promote the high-quality development of education and assistance in higher vocational colleges in the new era.